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OUR FOCUS is bringing innovative technology to patient care.

Molecular Pathology Laboratory Network (MPLN) is a leader in laboratory medicine, hematopathology, solid tumor oncology, immunology, and women’s health. Since our inception in 1989, we have pioneered the application of molecular pathology techniques in diagnostic and clinical research applications. 

Molecular Pathology Laboratory Network, Inc.

Experience MPLN's BIOPHARMADIGITAL PATHOLOGYMULTIPLEX IHCREFERENCE LABORATORYGENOMICCYTOGENETICS & FISH solutions.

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Biopharma Laboratory Support

  • Over 20 years of experience in biopharma laboratory services
  • Completed 400+ Phase I-IV clinical trials studies 
  • Sophisticated approach to disease mechanisms and unique trial needs

Reference Laboratory Services

  • Leading specialty reference lab for 35+ years
  • Expertise in hematopathology, pathology, molecular diagnostics, infectious disease, women’s health, and more
  • CAP, CLIA, ISO 15189, and NYSDOH accredited 

Test Menu

  • User-friendly online test menu for quick access
  • Details on specimens, turnaround times, stability, transportation, and storage 
  • Comprehensive guide to our lab services and capabilities
Biopharma Lab
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01
Solid Tumor Analysis

Advanced molecular profiling and precise biomarker studies drive targeted therapies in solid tumors, enhancing personalized treatment strategies for cancers including NSCLC, head and neck, prostate, breast and ovarian cancers

02
Hematological Malignancies

Cutting-edge diagnostics and precise classification transform the management of blood cancers, offering tailored insights for effective treatment planning 
in conditions such as AML, MDS, CLL, and multiple myeloma

03
GI Pathology

Expert analysis in GI pathology delivers accurate diagnostics for liver diseases, NASH, prostate cancer, ulcerative colitis 
and urological conditions, providing critical insights for effective patient management and treatment

04
Digital Pathology

Benefit from seamless access to digital slides, enhanced cost-effectiveness and simplify slide retrieval. By embracing digital pathology, your clinical trials can achieve new heights of efficiency and success.

OUR SOLUTIONS

A Fully Integrated Approach

Experience Our Difference.

OUR FOCUS is bringing innovative technology to patient care. Molecular Pathology Laboratory Network (MPLN) is a leader in laboratory medicine, hematopathology, solid tumor oncology, immunology, and women’s health. Since our inception in 1989, we have pioneered the application of molecular pathology techniques in diagnostic and clinical research applications. 

OUR APPROACH offers a unique understanding of the disease mechanism, integrating data from anatomic, cellular, and molecular investigations to provide physicians and clinical research teams with actionable information for patient monitoring and treatment decisions.

OUR COMMITMENT is that our CAP/CLIA & ISO 15189 accredited Global Laboratory Network will deliver high-quality data, maintain exceptional customer service, and provide project management and data management services, making us the ideal partner to support clinical patient management and advance your new therapeutic and IVD/CDx medical device projects.

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LIS Blue - Laboratory Information System

Our LIS Blue is a fast, easy-to-use, secure, and accessible laboratory information system developed using the latest web technology.

Visit lis.mplnet.com

    Project Management

    Our project managers have strong scientific backgrounds and extensive experience in complex research-based clinical trials. They collaborate with our scientific operations, client services, and commercial operations teams to deliver high-quality, regulatory-compliant testing results on time at every project step.

    Key Features

    • Studies are typically set up within 8 to 12 weeks of contract signature

    Benefits

    • Responsive communication with the scientific and operational teams

    Data Management

    The key to a successful clinical trial is accurate, clean, quality data. Our team of data managers provides you with data in customized formats exported to your data management teams from our in-house laboratory information system (LIS).

    Key Features

    • Access to dedicated and experienced data specialists upon contract award
    • Customized reports are agreed upon in study-specific data transfer agreement
    • Flexible data exports and data transfers

    Benefits

    • Real-time reports for your data and project teams to aid in patient management
    • Guaranteed data integrity and quality
    • Improved decision-making and enhanced patient safety
    • Timely access to accurate, clean data for intermediate or final database lock
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    Genomic Solutions

    Genomic Solutions

    Genomic testing delivers powerful, patient-specific insights that guide precision oncology and inform the next generation of targeted therapies.

    Our genomic testing options uncover critical genetic markers that drive disease progression and influence individual treatment responses. This empowers healthcare professionals to create more precise, tailored treatment plans, optimizing medical management based on each patient’s genetic profile[click here to view testing options].

    DNA Solutions – WGS*, WGMS*, WES*, TSO Comp, Pillar OncoRevealSolid Tumor, Pillar Myeloid
    RNA Solutions – Total RNA-Seq*, RNA exome*, mRNA*
    Liquid Biopsy Solutions – PGDx elio™ plasma complete*

    Key Features

    • Targeted NGS panels, including FDA-approved assays with companion diagnostic designations.
    • Customized bioinformatics and reporting solutions.
    • Robust assay   to accommodate low-yielding biopsy material
    • Streamlined wet lab processes to meet screening window timelines

    Benefits

    • Identify variants along with key biomarker signatures
    • Save time and money by assessing multiple biomarkers in a single test
    • Enable targeted therapies with actionable, easy-to-interpret results
    • Assists in targeted patient stratification and recruitment
    • Accelerates the development of personalized medicine

    *Offered through fully accredited partner laboratories.

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    Digital Pathology

    Digital Pathology

    Digital pathology revolutionizes clinical trials by enhancing accessibility, cost-efficiency, compliance, and data management. MPLN’s comprehensive digital pathology services streamline clinical research, allowing for improved patient outcomes and operational efficiency.

    Key Features

    • Cloud-based image managementplatform allows seamless access to digital images from anywhere around the globe.
    • Validated diagnostic workflows for primary diagnosis.
    • Digital imageworkflowsthat streamlinelogistics and reduce the need for physical slide storage and transportation.
    • Digital image transfer services and long-term secure image storage options are available.

    Benefits

    • Allows key opinion leaders (KOL) and remote client pathologists to be utilized in clinical trial workflows.
    • Enables efficient centralized review with simultaneous pathologist viewing.
    • Reduces the costs associated with physical slidetransport and storage
    • Simplifies regulatory processes, ensuring fasterand more accurate FDA submissions and audit readiness.
    • Prevents slide degradation or breakage, maintaining the quality of research datalong-term.
    • Enables broader patient recruitment by facilitating decentralized clinical trials for wider geographic participation, increasing patient recruitment and diversity.
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    Global Logistics

    Global Logistics

    Effective global logistics are the cornerstone of effective specialty laboratory testing supporting global clinical trials. With precious patient samples such as biopsy and bone marrow aspirates, ensuring samples reach the lab on time and within stability is paramount.

    Key Features

    • Partnerships with global specialist couriers and large integrators to support global studies and specialty shipping requirements
    • Ambient, refrigerated, frozen, and liquid nitrogen storage and shipment services available
    • Real-time or batched shipments based on your clinical trial’s individual needs
    • Secure, high-volume, redundant data storage solutions for digital pathology images
    • Expert advice for effective sample collection, handling, and transport
    • Accurate tracking and inventory for all clinical trial specimens

    Benefits

    • Safe and effective transport of specimens worldwide
    • Standardized procedures to reduce pre-analytical variability and ensure valid results
    • Centralized and harmonized specialty pathology testing supported
    • Reduced costs and maximized budgets with fully managed logistics from one trusted source
    • Readily available inventories, manifests, and shipments for timely study closeouts
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    Multiplex IHC clinical trial services

    IHC & Multiplex IHC

    Our advanced technology enables simultaneous visualization of single or multiple biomarkers within the same tissue section, delivering comprehensive insights and precise diagnostics. With unmatched expertise and cutting-edge technology, our team supports you in understanding complex tissue microenvironments, aiding patient stratification and treatment response prediction.

    Key Features

    • Over 200 IHC antibodies validated and ready for use in clinical trials [click here to view our IHC test menu].
    • Custom assay validation and flexible testing to meet unique research or clinical trial needs.
    • Simultaneous visualization ofmultiple biomarkers within the same tissue section.
    • Board-certified pathologists provide detailed data analysis and interpretation to ensure accurate results.

    Benefits

    • Gain comprehensive insights that lead to more precise diagnostics and better patient outcomes.
    • Enhanced ability to identify patient subgroups and better predict treatment responses.
    • Maximize information from small biopsy samples. (i.e.,NSCLC)
    • Whether in biomarker discovery or clinical trials, our advanced technology supports a range of applications, helping you unlock the full potential of your tissue samples.
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    Cytogenetics FISH - clinical trial services

    Cytogenetics & FISH

    We offer a comprehensive range of chromosome analysis and fluorescent in situ hybridization (FISH) testing with industry-leading turnaround times and global coverage. Our board-certified lab directors and experienced cytogenetic technologists ensure accurate, efficient, and competitively priced testing with the highest quality of service.

    Key Features

    • Extensive FISH menu of over 40 loci and disease-specific panels detecting gene amplifications, deletions, translocations, and inversions [click here to view testing menu].
    • Testing is available on bone marrow, blood, and FFPE tissue samples.
    • Comprehensive chromosome analysis testing for oncology, infertility, recurrent pregnancy loss, and congenital disorders.
    • Fully harmonized services at accredited partner labs to support global clinical trials.

    Specialized Offerings:

    • Plasma cell enrichment for plasma disorders
    • Stat turnaround for PML::RARA and acute myeloid leukemia
    • Bladder cancer urine analysis
    • Custom FISH assay validation services

    Benefits:

    • Rapid, precise results that are critical for diagnosis and treatment.
    • Achieve comprehensive coverage for key genes indicated in the diagnosis and prognosis of hematological malignancies per the current WHO, NCCN, and ELN guidelines.
    • Expert-driven testing with board-certified experts ensures the highest accuracy.
    • Tailored assays and solutions to meet unique clinical trial needs.
    • Faster diagnostics to support timely treatment decisions.
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